BACKGROUND: The prevalence of unruptured intracranial aneurysms (UIA) in females who smoke cigarettes and the association between smoking and hypertension with purely incidental UIAs have been unexplored.<\/p>\n
OBJECTIVE: To obtain the prevalence of UIA among females and to assess the relationship between smoking and hypertension with a diagnosis of incidental UIAs.<\/p>\n
METHODS: A nested case-control study from a cohort of female patients aged between 30 and 60 yr with a brain magnetic resonance angiography (MRA) between 2016 and 2018. Incidental UIAs were compared to patients with normal MRAs. Smoking was characterized as never or former\/current smokers. A logistic regression was used to evaluate the association between smoking, hypertension, or both, with a diagnosis of incidental UIAs.<\/p>\n
RESULTS: A total of 1977 patients had a brain MRA between 2016 and 2018. From 1572 nonsmoker patients, we encountered 30 with an UIA (prevalence: 1.9%). There were 405 patients with a positive smoking history, and 77 patients harbored an UIA (prevalence: 19%). Of 64 aneurysm patients and 130 random controls eligible for the case control, aneurysm patients were more likely to have a positive smoking history and hypertension compared with healthy controls (60% vs 18%, P\u2264.001; 44% vs 14%, P\u2264.001). A multivariable analysis demonstrated a significant association between a smoking history, hypertension, or both factors with an incidental UIA (odds ratio [OR] 5.8 CI 1.22-11.70; OR 3.8 CI 2.31-14.78; OR 12.6 CI 4.38-36.26; respectively).<\/p>\n
CONCLUSION: Females who smoke cigarettes have a higher prevalence of UIAs than the general population. Smoking confers a higher risk for having a silent UIA, aggravated by hypertension. This population is an ideal target for potential screening.<\/p>\n
\u200d<\/p>\n
(DOI: 10.1093\/neuros\/nyaa227).<\/p>\n","protected":false},"excerpt":{"rendered":"
BACKGROUND: The prevalence of unruptured intracranial aneurysms (UIA) in females who smoke cigarettes and the association between smoking and hypertension with purely incidental UIAs have…<\/p>\n","protected":false},"author":1,"featured_media":437,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/dev.herramientasvirtuales.com\/cienhus\/wp-json\/wp\/v2\/posts\/436"}],"collection":[{"href":"https:\/\/dev.herramientasvirtuales.com\/cienhus\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dev.herramientasvirtuales.com\/cienhus\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dev.herramientasvirtuales.com\/cienhus\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/dev.herramientasvirtuales.com\/cienhus\/wp-json\/wp\/v2\/comments?post=436"}],"version-history":[{"count":1,"href":"https:\/\/dev.herramientasvirtuales.com\/cienhus\/wp-json\/wp\/v2\/posts\/436\/revisions"}],"predecessor-version":[{"id":438,"href":"https:\/\/dev.herramientasvirtuales.com\/cienhus\/wp-json\/wp\/v2\/posts\/436\/revisions\/438"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/dev.herramientasvirtuales.com\/cienhus\/wp-json\/wp\/v2\/media\/437"}],"wp:attachment":[{"href":"https:\/\/dev.herramientasvirtuales.com\/cienhus\/wp-json\/wp\/v2\/media?parent=436"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dev.herramientasvirtuales.com\/cienhus\/wp-json\/wp\/v2\/categories?post=436"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dev.herramientasvirtuales.com\/cienhus\/wp-json\/wp\/v2\/tags?post=436"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}